Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585212 | 0.91 | OPRM1 (0.41) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL8992298 | 0.90 | OPRM1 (0.41) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL9586032 | 0.82 | ALOX15 (0.40) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL9587286 | 0.81 | OPRM1 (0.42) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL9807220 | 0.76 | OPRM1 (0.52) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| Pramiverine SCHEMBL24038 | 0.75 | GAA (0.47) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| Pramiverine SCHEMBL10728097 | 0.74 | GAA (0.46) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL9586402 | 0.73 | ALDH1A1 (0.37) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL11763463 | 0.73 | MAPK1 (0.44) | OPRM1MAPK1SMN1; SMN2OPRL1ALOX15 | |
| SCHEMBL8101425 | 0.72 | OPRM1 (0.50) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445749-B1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-07-10 | — | — | EP | disclosed |