Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 7/20 | 0.35 |
| ▸ | MAOA | P21397 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586402 | 0.90 | ALDH1A1 (0.37) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL8992298 | 0.86 | OPRM1 (0.41) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL8992487 | 0.81 | OPRM1 (0.47) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL9586032 | 0.78 | ALOX15 (0.40) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL9585212 | 0.74 | OPRM1 (0.41) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL8992275 | 0.68 | MAOB (0.32) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL11763463 | 0.68 | MAPK1 (0.44) | OPRM1MAOBMAOADRD4KDM1A | |
| Hydrochloric Acid SCHEMBL8992323 | 0.67 | MAOB (0.33) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL9846435 | 0.67 | LMNA (0.33) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL7750182 | 0.67 | IDO1 (0.44) | GRIN2BMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256824-A | Anticholinergic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0445749-A1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |