Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.57 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 3/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.47 |
| ▸ | TDP2 | O95551 | 2/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | PRKACG | P22612 | 1/20 | 0.46 |
| ▸ | PRKACB | P22694 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992603 | 0.72 | PTPRC (0.50) | PTPN1DNMT1NSD2HKDC1APAF1 | |
| SCHEMBL23743472 | 0.68 | MAPT (0.51) | PTPN1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL7260223 | 0.65 | APAF1 (1.00) | PTPN1DNMT1NSD2HKDC1APAF1 | |
| SCHEMBL10153905 | 0.63 | BIRC5 (0.64) | PRKD3PRKCGPRKCBPRKCAPRKACA | |
| SCHEMBL170890 | 0.63 | BIRC5 (0.70) | PRKD3PRKCGPRKCBPRKCAPRKACA | |
| SCHEMBL13052919 | 0.63 | BIRC5 (0.59) | PRKD3PRKCGPRKCBPRKCAPRKACA | |
| SCHEMBL29475118 | 0.63 | BIRC5 (0.70) | PRKD3PRKCGPRKCBPRKCAPRKACA | |
| SCHEMBL10037145 | 0.62 | DNMT1 (0.77) | PTPN1DNMT1NSD2HKDC1APAF1 | |
| SCHEMBL4649553 | 0.62 | DNMT1 (0.83) | PTPN1DNMT1NSD2HKDC1APAF1 | |
| SCHEMBL20110565 | 0.62 | BIRC5 (0.44) | PRKD3PRKCGPRKCBPRKCAPRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560682-B1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | OREAL (FR) | 1996-08-07 | — | — | EP | disclosed |
| EP-0560682-A1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |