Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.33 |
| ▸ | DRD2 | P14416 | 8/20 | 0.33 |
| ▸ | HTR2A | P28223 | 8/20 | 0.33 |
| ▸ | DRD3 | P35462 | 8/20 | 0.33 |
| ▸ | DRD1 | P21728 | 4/20 | 0.33 |
| ▸ | HTR7 | P34969 | 4/20 | 0.33 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | DRD5 | P21918 | 3/20 | 0.33 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408765 | 0.90 | DRD2 (0.37) | DRD2DRD3HTTNPC1RAB9A | |
| SCHEMBL8660335 | 0.88 | PPARD (0.36) | HTTMAPTL3MBTL1PPARDALDH1A1 | |
| SCHEMBL8658661 | 0.87 | PPARD (0.39) | HTR1ADRD2HTR2ADRD3HTT | |
| SCHEMBL8656070 | 0.87 | ALDH1A1 (0.38) | HTTNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8655768 | 0.87 | ALDH1A1 (0.39) | DRD2DRD3HTTNPC1MAPT | |
| SCHEMBL8658134 | 0.86 | FFAR4 (0.37) | HTTPPARDPPARA | |
| SCHEMBL8657516 | 0.86 | LMNA (0.33) | HTTALDH1A1 | |
| SCHEMBL8656652 | 0.85 | MCL1 (0.37) | HTTNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8657375 | 0.85 | PPARA (0.41) | DRD2DRD3HTTPPARDPPARA | |
| SCHEMBL8661839 | 0.84 | PPARD (0.38) | HTR1ADRD2HTR2ADRD3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722430-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1996004228-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-02-15 | — | — | WO | disclosed |