SCHEMBL8408765

SCHEMBL8408765

ClC(Cl)=CCOc1cc(Cl)c(OCCCSc2ccc(Cl)cc2)c(Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.37
DRD4 P21917 2/20 0.37
DRD3 P35462 1/20 0.36
KDM4E B2RXH2 5/20 0.36
ALDH1A1 P00352 5/20 0.36
PKM P14618 2/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
HPGD P15428 3/20 0.34
MAPT P10636 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8655768 0.96 ALDH1A1 (0.39) DRD2DRD4DRD3KDM4EALDH1A1
SCHEMBL8658413 0.94 HPGD (0.39) DRD2DRD4KDM4EALDH1A1HPGD
SCHEMBL8660335 0.90 PPARD (0.36) KDM4EALDH1A1MAPTL3MBTL1HTT
SCHEMBL8992644 0.90 HTR1A (0.33) DRD2DRD3ALDH1A1MAPTL3MBTL1
SCHEMBL8656070 0.89 ALDH1A1 (0.38) KDM4EALDH1A1HPGDMAPTL3MBTL1
SCHEMBL8661988 0.89 DRD2 (0.36) DRD2DRD4DRD3KDM4EALDH1A1
SCHEMBL8657516 0.88 LMNA (0.33) ALDH1A1HTTLMNA
SCHEMBL8656652 0.87 MCL1 (0.37) KDM4EALDH1A1MAPTL3MBTL1HTT
SCHEMBL8658661 0.87 PPARD (0.39) DRD2DRD3HTTLMNASMN1; SMN2
SCHEMBL8661323 0.87 DHFR (0.37) DRD2DRD4DRD3KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5872137-A AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-16 US disclosed
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 EP disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 WO disclosed