Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453855 | 0.86 | CYP2A6 (0.38) | CYP2D6TSHRNPC1ALDH1A1HPGD | |
| SCHEMBL17514642 | 0.84 | AR (0.34) | — | |
| SCHEMBL17514975 | 0.83 | MAPK10 (0.39) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL17514753 | 0.83 | OXTR (0.34) | PDCD1LG2CD274 | |
| SCHEMBL164522 | 0.79 | — | — | |
| SCHEMBL17514792 | 0.78 | ORAI1 (0.34) | MAPK1TSHRHPGD | |
| SCHEMBL17514517 | 0.77 | PTPN1 (0.36) | MAPK1PDE3AALDH1A1LMNAMAPT | |
| SCHEMBL9393668 | 0.77 | CRHR1 (0.44) | SLC6A3NPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL15636895 | 0.76 | NOTUM (0.39) | NUDT1NOTUMP2RX7IDO1CYP2D6 | |
| SCHEMBL17514995 | 0.74 | HTR1A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602478-B1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 1996-07-31 | — | — | EP | disclosed |