Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790729 | 0.83 | HCAR3 (0.39) | LMNACYP1A2CYP3A4MAOAPDE4D | |
| SCHEMBL594840 | 0.82 | HDAC1 (0.48) | LMNACYP1A2CYP3A4MAOAPDE4D | |
| SCHEMBL29394454 | 0.81 | HCAR3 (0.36) | LMNACYP1A2CYP3A4MAOANPC1 | |
| SCHEMBL56808 | 0.79 | TTK (0.37) | ALDH1A1RAB9AKDM4E | |
| SCHEMBL2791067 | 0.79 | DGAT1 (0.42) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL8993135 | 0.77 | MAPT (0.49) | LMNACYP1A2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8992720 | 0.77 | MAOA (0.36) | LMNACYP1A2CYP3A4MAOAPDE4D | |
| SCHEMBL2792080 | 0.77 | CA12 (0.36) | CYP1A2ALDH1A1SMN1; SMN2HCAR3KDM4E | |
| SCHEMBL477388 | 0.77 | HCAR3 (0.38) | ALDH1A1MAPTHCAR3KDM4EKMT2A | |
| SCHEMBL19418024 | 0.76 | CA12 (0.35) | ALDH1A1TSHRHCAR3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601302-B1 | Hair dyeing composition containing 3-pyridinazo dyes and novel 3-pyridazo dyes | WELLA AG (DE) | 1996-07-10 | — | — | EP | disclosed |
| EP-0601302-A1 | Hair dyeing composition containing 3-pyridinazo dyes and novel 3-pyridazo dyes | Wella Aktiengesellschaft (DE) | 1994-06-15 | — | — | EP | disclosed |