Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477465 | 0.81 | CYP2C19 (0.50) | MAPTRAB9AKDM4ENPC1PKM | |
| SCHEMBL2790902 | 0.80 | GAA (0.53) | MAPTRAB9AKDM4ENPC1PKM | |
| SCHEMBL8993067 | 0.79 | MAPT (0.43) | MAPTRAB9AKDM4ENPC1PKM | |
| SCHEMBL8751720 | 0.79 | ALDH1A1 (0.57) | MAPTKDM4EPKMGAAAR | |
| SCHEMBL8992767 | 0.77 | LMNA (0.42) | MAPTRAB9AKDM4ENPC1CYP1A2 | |
| SCHEMBL14472592 | 0.75 | MAPT (0.42) | MAPTRAB9AKDM4ENPC1PKM | |
| SCHEMBL28254387 | 0.75 | PKM (0.56) | MAPTRAB9AKDM4ENPC1PKM | |
| SCHEMBL4187236 | 0.75 | MAPT (0.51) | MAPTRAB9AKDM4ENPC1CYP2C19 | |
| SCHEMBL3313819 | 0.74 | MAPT (0.60) | MAPTRAB9AKDM4ENPC1POLB | |
| SCHEMBL933269 | 0.74 | PKM (0.57) | MAPTRAB9AKDM4ENPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601302-B1 | Hair dyeing composition containing 3-pyridinazo dyes and novel 3-pyridazo dyes | WELLA AG (DE) | 1996-07-10 | — | — | EP | disclosed |
| EP-0601302-A1 | Hair dyeing composition containing 3-pyridinazo dyes and novel 3-pyridazo dyes | Wella Aktiengesellschaft (DE) | 1994-06-15 | — | — | EP | disclosed |