Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 3/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993204 | 0.87 | SMN1; SMN2 (0.52) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL8992832 | 0.83 | RAB9A (0.52) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL8992809 | 0.81 | HSP90AB1 (0.41) | ALDH1A1KDM4EMAPTKDRRET | |
| SCHEMBL8993229 | 0.80 | BRS3 (0.52) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL8992780 | 0.78 | BRS3 (0.54) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL8993105 | 0.71 | BRS3 (0.45) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL8993059 | 0.71 | CHEK2 (0.43) | ALDH1A1KDRRETLMNACYP1A2 | |
| SCHEMBL8992993 | 0.71 | NPC1 (0.68) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL9165136 | 0.70 | RAB9A (0.52) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL8992991 | 0.69 | NPC1 (0.57) | ALDH1A1KDM4EMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |