Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992794 | 0.81 | ALDH1A1 (0.43) | RETKDM4EMAPTFYNKDR | |
| SCHEMBL8992965 | 0.79 | GPR119 (0.41) | KDM4EMAPTKDRALDH1A1HSD17B10 | |
| SCHEMBL8992922 | 0.78 | GPR119 (0.43) | RETMAPK1FYNKDRALDH1A1 | |
| SCHEMBL8993204 | 0.76 | SMN1; SMN2 (0.52) | KDM4EMAPTKDRALDH1A1TSHR | |
| SCHEMBL8992990 | 0.76 | KMT2A (0.48) | KDM4EMAPTMAPK1KDRALDH1A1 | |
| SCHEMBL8993148 | 0.76 | KMT2A (0.41) | MAPTMAPK1KDRMEN1HPGD | |
| SCHEMBL9215696 | 0.75 | RAB9A (0.42) | KDM4EMAPTKDRALDH1A1HSD17B10 | |
| SCHEMBL9215756 | 0.73 | SRC (0.45) | KDM4EMAPTKDRALDH1A1MEN1 | |
| SCHEMBL9221670 | 0.70 | RAB9A (0.45) | KDM4EMAPTKDRALDH1A1MEN1 | |
| SCHEMBL9213350 | 0.70 | RAB9A (0.52) | KDM4EMAPTL3MBTL1KDRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |