Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | BRS3 | P32247 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993229 | 0.89 | BRS3 (0.52) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL8992780 | 0.87 | BRS3 (0.54) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL8992993 | 0.86 | NPC1 (0.68) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL8992794 | 0.83 | ALDH1A1 (0.43) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL9165136 | 0.83 | RAB9A (0.52) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL8992774 | 0.81 | RAB9A (0.50) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL8992889 | 0.81 | HCAR2 (0.50) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL19668727 | 0.78 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL4708839 | 0.78 | PTPN1 (0.44) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL8993105 | 0.77 | BRS3 (0.45) | RAB9ASMN1; SMN2NPC1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |