Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101334 | 0.88 | TAAR1 (0.55) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL8992841 | 0.85 | CALM1 (0.50) | LTA4H | |
| SCHEMBL8992807 | 0.83 | CNR2 (0.46) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL8993396 | 0.83 | CNR2 (0.48) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL14191204 | 0.83 | LTA4H (0.70) | LTA4HMTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL8992958 | 0.83 | LTA4H (0.59) | LTA4HTAAR1IDO1AGXTMAOB | |
| SCHEMBL2099512 | 0.82 | CHRM2 (0.66) | LTA4HCHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL8784075 | 0.82 | TAAR1 (0.49) | CHRM2CHRM1CHRM3TAAR1IDO1 | |
| SCHEMBL31739258 | 0.81 | LTA4H (0.67) | LTA4HMTNR1AMTNR1BCHRM2CHRM1 | |
| SCHEMBL2092574 | 0.81 | LTA4H (0.67) | LTA4HMTNR1AMTNR1BCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1036919-C | Pyrazole condensed ring derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMA CO LTD (JP) | 1998-01-07 | — | — | CN | disclosed |
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| CN-1089609-A | Pyrazole-fused ring derivatives, its manufacture method and male hormone inhibitor | OTSUKA PHARMA CO LTD (JP) | 1994-07-20 | — | — | CN | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |