SCHEMBL8993154

SCHEMBL8993154

C#CC[SiH2]c1cccc(C)c1C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.34
ATM Q13315 1/20 0.34
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9217674 0.77 TRPA1 (0.41) TRPA1ATMCYP1A2CYP2A6
SCHEMBL10440548 0.75 TRPA1 (0.39) TRPA1ATMCYP1A2CYP2A6
SCHEMBL7033569 0.74 TRPA1 (0.38) TRPA1ATMCYP1A2CYP2A6
SCHEMBL852173 0.74 TRPA1 (0.38) TRPA1ATMCYP1A2CYP2A6
SCHEMBL10523368 0.74 TRPA1 (0.38) TRPA1ATMCYP1A2CYP2A6
SCHEMBL6340796 0.74 TRPA1 (0.43) TRPA1ATMCYP1A2CYP2A6
SCHEMBL587377 0.74 TRPA1 (0.38) TRPA1ATMCYP1A2CYP2A6
SCHEMBL9343766 0.74 TRPA1 (0.38) TRPA1ATMCYP1A2CYP2A6
SCHEMBL1470830 0.71 TRPA1 (0.40) TRPA1ATMCYP1A2CYP2A6
SCHEMBL11206939 0.70 TRPA1 (0.36) TRPA1ATMCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5494989-A GAS AND VAPOR SEPARATION BEND RESEARCH, INC. (US) 1996-02-27 US disclosed