Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11159464 | 0.86 | SMN1; SMN2 (0.52) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL6815303 | 0.84 | LMNA (0.58) | HSP90AA1CA1CA2LOXL2TSHR | |
| SCHEMBL8993073 | 0.82 | MAPT (0.51) | CA1CA2ALDH1A1KMT2ALOXL2 | |
| SCHEMBL27168760 | 0.82 | LOXL2 (0.51) | CA1CA2ALDH1A1KMT2ALOXL2 | |
| SCHEMBL15778501 | 0.81 | ALDH1A1 (0.53) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL6825689 | 0.81 | CA1 (0.56) | HSP90AA1CA1CA2ALDH1A1MEN1 | |
| SCHEMBL2332196 | 0.80 | ALDH1A1 (0.49) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL38658158 | 0.80 | NR4A2 (0.57) | ALDH1A1MEN1KMT2ATSHRNPC1 | |
| SCHEMBL20236579 | 0.80 | HIF1A (0.62) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL7651523 | 0.80 | ALDH1A1 (0.51) | CA1CA2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |