Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490239 | 0.81 | GAA (0.41) | TSHRLMNATDP1L3MBTL1 | |
| SCHEMBL5330089 | 0.69 | FABP5 (0.43) | TSHR | |
| SCHEMBL18170903 | 0.68 | FABP5 (0.44) | SMN1; SMN2 | |
| SCHEMBL6938982 | 0.68 | MAPT (0.39) | LMNAL3MBTL1 | |
| Butylparaben SCHEMBL23458813 | 0.68 | ESR1 (0.79) | TSHRLMNAESR1CYP1A2CYP2D6 | |
| Benzoic Acid SCHEMBL2470729 | 0.68 | ALDH1A1 (0.62) | PLA2G4BTSHRTP53LMNAMAPK1 | |
| Benzoic Acid SCHEMBL21332486 | 0.68 | LMNA (0.71) | TSHRTP53LMNAESR1CYP1A2 | |
| SCHEMBL29042899 | 0.68 | TSHR (0.54) | TSHRTP53LMNAESR1CYP1A2 | |
| Terephthalic Acid SCHEMBL21044732 | 0.68 | TSHR (0.74) | PLA2G4BTSHRTP53LMNAESR1 | |
| SCHEMBL37477 | 0.68 | TSHR (0.74) | PLA2G4BTSHRTP53LMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | claimed |