Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655187 | 0.87 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL8658108 | 0.84 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL12570643 | 0.79 | PTGS2 (0.58) | PTGS2PTGS1GAAPSIP1 | |
| SCHEMBL7865484 | 0.78 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL8654932 | 0.78 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL8652595 | 0.77 | PTGS2 (0.47) | PTGS2PTGS1 | |
| Fluoresone SCHEMBL24999 | 0.77 | PSIP1 (0.58) | PTGS2GAAPSIP1 | |
| SCHEMBL8652996 | 0.77 | PTGS2 (0.59) | PTGS2PTGS1GAA | |
| SCHEMBL8654161 | 0.74 | PTGS2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL8655287 | 0.74 | PTGS2 (0.47) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724566-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011883-A1 | 1,2-DIARYLCYCLOPENTENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-05-04 | — | — | WO | disclosed |