Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.58 |
| ▸ | PSIP1 | O75475 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoresone SCHEMBL24999 | 0.93 | PSIP1 (0.58) | PTGS2PSIP1GAAHTTKMT2A | |
| SCHEMBL7865484 | 0.84 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL10455034 | 0.81 | PSIP1 (0.74) | PSIP1GAALMNAHTTSMN1; SMN2 | |
| SCHEMBL5134257 | 0.80 | PSIP1 (0.74) | PTGS2PSIP1GAA | |
| SCHEMBL293991 | 0.80 | PSIP1 (0.74) | PTGS2PSIP1GAA | |
| SCHEMBL8993411 | 0.79 | PTGS2 (0.46) | PTGS2PSIP1GAAPTGS1 | |
| SCHEMBL1368369 | 0.78 | L3MBTL1 (0.53) | PTGS2GAAHTTKMT2APAX8 | |
| SCHEMBL5049079 | 0.78 | PSIP1 (0.52) | PTGS2PSIP1GAAKIF11PTGS1 | |
| SCHEMBL5133527 | 0.78 | PSIP1 (0.52) | PTGS2PSIP1GAAKIF11PTGS1 | |
| SCHEMBL904021 | 0.77 | KIF11 (0.57) | PTGS2PSIP1GAAKIF11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110135604-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110135604-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | PTGS2 3377/4885PSIP1 1500/4885GAA 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.