Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993511 | 0.79 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL8993508 | 0.66 | IDO1 (0.46) | SLC6A4MEN1KMT2ACYP2D6ALDH1A1 | |
| SCHEMBL8993465 | 0.66 | IDO1 (0.46) | SLC6A4MEN1KMT2ACYP2D6ALDH1A1 | |
| SCHEMBL24017025 | 0.66 | MMP13 (0.43) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL8993638 | 0.64 | GAA (0.37) | SLC6A2SLC6A3GAAALDH1A1MAPT | |
| SCHEMBL8846878 | 0.64 | SMN1; SMN2 (0.53) | SLC6A2SLC6A3MEN1KMT2ADDB1 | |
| SCHEMBL6555228 | 0.64 | SMN1; SMN2 (0.53) | SLC6A2SLC6A3MEN1KMT2ADDB1 | |
| SCHEMBL8846872 | 0.64 | SMN1; SMN2 (0.53) | SLC6A2SLC6A3MEN1KMT2ADDB1 | |
| SCHEMBL18025750 | 0.63 | PDE4A (0.51) | SLC6A2SLC6A4SLC6A3MAPTMMP13 | |
| Hydrochloric Acid SCHEMBL8993466 | 0.62 | SMN1; SMN2 (0.52) | SLC6A2SLC6A3MEN1KMT2ADDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574169-A | CHOLECYSTOKININ ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |