Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | UBE2I | P63279 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.32 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.32 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993465 | 0.83 | IDO1 (0.46) | MAPTKDM4EIDO1MTNR1ACYP1A2 | |
| SCHEMBL8993508 | 0.83 | IDO1 (0.46) | MAPTKDM4EIDO1MTNR1ACYP1A2 | |
| SCHEMBL24017027 | 0.62 | MTNR1A (0.49) | MAPTKDM4EIDO1MTNR1AALDH1A1 | |
| SCHEMBL8993479 | 0.62 | IDO1 (0.40) | MAPTKDM4EIDO1GSK3BMTNR1A | |
| SCHEMBL11210866 | 0.59 | PBRM1 (0.35) | GAAMETAP2PBRM1ALDH1A1NPC1 | |
| SCHEMBL4106140 | 0.59 | CYP2A6 (0.63) | MAPTKDM4EMAOATDP1CYP1A2 | |
| SCHEMBL8993589 | 0.58 | SLC6A3 (0.51) | GAAMAPTKDM4ESLC6A3CACNB4 | |
| SCHEMBL13035722 | 0.58 | MEN1 (0.67) | GAAMAPTKDM4EPOLBTDP1 | |
| SCHEMBL9643984 | 0.57 | CYP2A6 (0.55) | GAAMAPTKDM4EMAOAMAOB | |
| Ammonia Solution, Strong SCHEMBL27937808 | 0.57 | CYP2A6 (0.61) | MAPTKDM4EMAOATDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574169-A | CHOLECYSTOKININ ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5399708-A | Cholecystokinin and gastrin antagonists; gastrointestinal and central nervous system disorders | ELI LILLY AND COMPANY (US) | 1995-03-21 | — | — | US | disclosed |