Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993465 | 1.00 | IDO1 (0.46) | IDO1MTNR1AMAPTALDH1A1HPGD | |
| SCHEMBL8993638 | 0.83 | GAA (0.37) | IDO1MTNR1AMAPTALDH1A1KDM4E | |
| SCHEMBL8993479 | 0.76 | IDO1 (0.40) | IDO1MTNR1AMAPTALDH1A1HPGD | |
| SCHEMBL24017027 | 0.73 | MTNR1A (0.49) | IDO1MTNR1AMAPTALDH1A1HPGD | |
| SCHEMBL6380847 | 0.67 | IDO1 (0.54) | IDO1MTNR1AMAPTALDH1A1HPGD | |
| SCHEMBL8993454 | 0.66 | SLC6A2 (0.41) | MAPTALDH1A1CYP2D6MEN1KMT2A | |
| SCHEMBL10822158 | 0.64 | IDO1 (0.55) | IDO1MTNR1AMAPTALDH1A1HPGD | |
| SCHEMBL18025752 | 0.64 | IDO1 (0.51) | IDO1MTNR1AMAPTALDH1A1HPGD | |
| SCHEMBL30588975 | 0.64 | IDO1 (0.55) | IDO1MTNR1AMAPTALDH1A1HPGD | |
| SCHEMBL27705886 | 0.64 | MAPK1 (0.43) | IDO1MTNR1AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574169-A | CHOLECYSTOKININ ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5399708-A | Cholecystokinin and gastrin antagonists; gastrointestinal and central nervous system disorders | ELI LILLY AND COMPANY (US) | 1995-03-21 | — | — | US | disclosed |