Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555228 | 0.83 | SMN1; SMN2 (0.53) | SLC6A2SLC6A3GAAMAPTCYP3A4 | |
| SCHEMBL8846878 | 0.83 | SMN1; SMN2 (0.53) | SLC6A2SLC6A3GAAMAPTCYP3A4 | |
| SCHEMBL8846872 | 0.83 | SMN1; SMN2 (0.53) | SLC6A2SLC6A3GAAMAPTCYP3A4 | |
| Hydrochloric Acid SCHEMBL8993466 | 0.81 | SMN1; SMN2 (0.52) | SLC6A2SLC6A3GAAMAPTCYP3A4 | |
| SCHEMBL8993454 | 0.79 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3GAAMAPT | |
| SCHEMBL8993589 | 0.78 | SLC6A3 (0.51) | SLC6A2SLC6A4SLC6A3GAAMAPT | |
| SCHEMBL8993503 | 0.78 | ALDH1A1 (0.47) | GAAMAPTALDH1A1KDM4EDDB1 | |
| SCHEMBL8993513 | 0.69 | HTR2C (0.43) | GAA | |
| SCHEMBL24017025 | 0.67 | MMP13 (0.43) | SLC6A2SLC6A4SLC6A3GAAMAPT | |
| SCHEMBL6544579 | 0.67 | MAPT (0.49) | SLC6A2SLC6A3GAAMAPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574169-A | CHOLECYSTOKININ ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |