Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091735 | 0.77 | SLC6A3 (0.40) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5179397 | 0.76 | SMN1; SMN2 (0.43) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL25935883 | 0.71 | DDB1 (0.43) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL22918239 | 0.68 | CHRNB2 (0.41) | ALDH1A1SMN1; SMN2DDB1CRBN | |
| SCHEMBL11444335 | 0.67 | ALDH2 (0.55) | DDB1CRBNFPR1FPR2 | |
| SCHEMBL25935699 | 0.67 | CRBN (0.65) | DDB1CRBN | |
| SCHEMBL7980719 | 0.67 | CYP19A1 (0.46) | DDB1CRBN | |
| SCHEMBL15493032 | 0.66 | DDB1 (0.37) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12676475 | 0.66 | MAPT (0.57) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6178200 | 0.64 | MKNK1 (0.48) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574169-A | CHOLECYSTOKININ ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |