Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555228 | 0.79 | SMN1; SMN2 (0.53) | ALDH1A1DDB1CRBNLMNAGAA | |
| SCHEMBL8846878 | 0.79 | SMN1; SMN2 (0.53) | ALDH1A1DDB1CRBNLMNAGAA | |
| SCHEMBL8846872 | 0.79 | SMN1; SMN2 (0.53) | ALDH1A1DDB1CRBNLMNAGAA | |
| Hydrochloric Acid SCHEMBL8993466 | 0.78 | SMN1; SMN2 (0.52) | ALDH1A1DDB1CRBNLMNAGAA | |
| SCHEMBL8993589 | 0.78 | SLC6A3 (0.51) | ALDH1A1GRM5GAAKDM4EHPGD | |
| SCHEMBL8993511 | 0.78 | SLC6A2 (0.45) | ALDH1A1DDB1CRBNGAAKDM4E | |
| SCHEMBL5021757 | 0.71 | GRM5 (0.77) | ALDH1A1HTR2CGRM5LMNAGAA | |
| SCHEMBL6385829 | 0.68 | DDB1 (0.55) | ALDH1A1DDB1CRBNHTR2CGAA | |
| SCHEMBL7561637 | 0.67 | EDNRA (0.76) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL10972682 | 0.67 | ALDH1A1 (0.65) | ALDH1A1DDB1CRBNHTR2CGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574169-A | CHOLECYSTOKININ ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |