Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846872 | 0.83 | SMN1; SMN2 (0.53) | SLC6A3SLC6A2MAPTALDH1A1GAA | |
| SCHEMBL8846878 | 0.83 | SMN1; SMN2 (0.53) | SLC6A3SLC6A2MAPTALDH1A1GAA | |
| SCHEMBL6555228 | 0.83 | SMN1; SMN2 (0.53) | SLC6A3SLC6A2MAPTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL8993466 | 0.81 | SMN1; SMN2 (0.52) | SLC6A3SLC6A2MAPTALDH1A1GAA | |
| SCHEMBL8993511 | 0.78 | SLC6A2 (0.45) | SLC6A3SLC6A2MAPTALDH1A1SLC6A4 | |
| SCHEMBL8993503 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1HPGDGAAKDM4E | |
| SCHEMBL10406907 | 0.71 | SLC6A3 (0.54) | SLC6A3SLC6A2MAPTALDH1A1HPGD | |
| SCHEMBL8993513 | 0.69 | HTR2C (0.43) | TSHRGAAHTT | |
| SCHEMBL10406906 | 0.69 | SLC6A3 (0.48) | SLC6A3SLC6A2MAPTALDH1A1HPGD | |
| SCHEMBL6544579 | 0.67 | MAPT (0.49) | SLC6A3SLC6A2MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574169-A | CHOLECYSTOKININ ANTAGONIST | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |