Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 6/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993965 | 0.97 | ALDH1A1 (0.38) | L3MBTL1ALOX5SMN1; SMN2GALR3CYP1A2 | |
| SCHEMBL8994021 | 0.86 | PSEN1 (0.33) | L3MBTL1ALDH1A1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL8993977 | 0.81 | L3MBTL1 (0.38) | L3MBTL1ALOX5SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL195345 | 0.79 | MEN1 (0.45) | L3MBTL1ALDH1A1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL8993946 | 0.75 | CYP1A2 (0.46) | L3MBTL1ALOX5SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL743427 | 0.73 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1KMT2AMAPK1TDP1 | |
| SCHEMBL5512903 | 0.73 | MEN1 (0.44) | L3MBTL1ALDH1A1KMT2ATDP1CYP2C9 | |
| SCHEMBL14570550 | 0.72 | SMN1; SMN2 (0.51) | L3MBTL1ALOX5SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL8993953 | 0.72 | CYP1A2 (0.45) | L3MBTL1ALOX5SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL21533566 | 0.71 | ALOX5 (0.42) | L3MBTL1ALOX5SMN1; SMN2CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510668-A2 | Phenothiazine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-28 | — | — | EP | claimed |
| US-5532171-A | PHENOTHIAZINE DYES FOR PHOTODYNAMIC THERAPY OF CANCER OR IMMUNOASSAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5344928-A | Phenothiazine compounds for cancer treatment or immunoassay using chemiluminescence | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0510668-A2 | Phenothiazine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-28 | — | — | EP | disclosed |