Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | PPIB | P23284 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | PPIG | Q13427 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993953 | 0.99 | CYP1A2 (0.45) | CYP1A2CYP3A4LMNAMAOASMN1; SMN2 | |
| SCHEMBL8993946 | 0.94 | CYP1A2 (0.46) | CYP1A2CYP3A4LMNAMAOASMN1; SMN2 | |
| SCHEMBL21471472 | 0.85 | MLYCD (0.43) | LMNAALDH1A1TSHRHSD17B10KMT2A | |
| SCHEMBL8993951 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1TDP1 | |
| SCHEMBL7714031 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1TDP1 | |
| SCHEMBL21471540 | 0.83 | CYP1A2 (0.42) | CYP1A2CYP3A4LMNAMAOASMN1; SMN2 | |
| SCHEMBL7712007 | 0.83 | KMT2A (0.49) | CYP1A2CYP3A4SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL6611276 | 0.82 | SMN1; SMN2 (0.53) | CYP1A2CYP3A4LMNAMAOASMN1; SMN2 | |
| SCHEMBL14570550 | 0.82 | SMN1; SMN2 (0.51) | CYP1A2CYP3A4SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL22454703 | 0.80 | L3MBTL1 (0.45) | CYP1A2CYP3A4SMN1; SMN2CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532171-A | PHENOTHIAZINE DYES FOR PHOTODYNAMIC THERAPY OF CANCER OR IMMUNOASSAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5344928-A | Phenothiazine compounds for cancer treatment or immunoassay using chemiluminescence | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0510668-A2 | Phenothiazine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-28 | — | — | EP | disclosed |