Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24378472 | 0.76 | MAPT (0.37) | HASPINTSHRALDH1A1LMNAMAPT | |
| SCHEMBL5644305 | 0.76 | KDM4E (0.34) | HASPINTSHRLMNA | |
| SCHEMBL3281314 | 0.72 | PKM (0.41) | HASPINTSHRALDH1A1LMNAMAPT | |
| SCHEMBL850564 | 0.72 | — | — | |
| SCHEMBL24378525 | 0.71 | ALDH1A1 (0.39) | HASPINALDH1A1 | |
| SCHEMBL10814834 | 0.69 | — | — | |
| SCHEMBL5609570 | 0.68 | TSHR (0.34) | TSHR | |
| SCHEMBL8994058 | 0.67 | APLNR (0.39) | ESR1ESR2PDCD1CD274 | |
| SCHEMBL12276078 | 0.65 | APLNR (0.43) | ESR1ESR2 | |
| SCHEMBL17044891 | 0.65 | APLNR (0.43) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502190-A | DEHYDROHALOGENATION IN THE PRESENCE OF PHASE TRANSFER CATALYST, SOLVENT AND ALKALI METAL HYDROXIDE | BAYER CORPORATION (US) | 1996-03-26 | — | — | US | disclosed |
| US-4729987-A | Insecticidal O,O-diethyl-O-(2-(1,1-dimethylethyl)-5-pyrimidinyl)-phosphorothioate | THE DOW CHEMICAL COMPANY (US) | 1988-03-08 | — | — | US | disclosed |
| US-4654329-A | Insecticidal, miticidal or nematocidal phosphorus esters of 5-pyrimidinols | THE DOW CHEMICAL COMPANY (US) | 1987-03-31 | — | — | US | disclosed |
| US-4429125-A | INSECTICIDES FOR APPLICATION TO SOILS | THE DOW CHEMICAL CO. (US) | 1984-01-31 | — | — | US | disclosed |
| EP-0004644-A2 | Pyrimidin(5)yl-(thiono)(thiol)-phosphoric(phosphonic) acid esters or amides, process for their preparation and their use as insecticides and acaricides | BAYER AG (DE) | 1979-10-17 | — | — | EP | disclosed |