Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913390 | 0.85 | ALDH1A1 (0.68) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL11484305 | 0.83 | CA2 (0.64) | TDP1TSHRALDH1A1MAPTPKM | |
| SCHEMBL11493058 | 0.82 | MAPT (0.55) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL11758589 | 0.81 | CASP6 (0.67) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL11486729 | 0.81 | ALDH1A1 (0.77) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL18780668 | 0.80 | ALDH1A1 (0.53) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL6516381 | 0.79 | MAPT (0.53) | TSHRALDH1A1MAPTPKMMEN1 | |
| SCHEMBL9464985 | 0.79 | CA9 (0.73) | TDP1ALDH1A1MAPTLMNAPKM | |
| SCHEMBL9517669 | 0.78 | MAPT (0.52) | TDP1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL11876416 | 0.78 | GPR35 (0.56) | TDP1TSHRALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956927-A | Benzimidazoles derivative, preparation method and its in application pharmaceutically | 北京诺诚健华医药科技有限公司 | 2019-07-02 | — | — | CN | disclosed |
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |
| US-4185018-A | Process for producing benzofurazan-1-oxides | CIBA-GEIGY CORPORATION (US) | 1980-01-22 | — | — | US | disclosed |