Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Butyric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL107185 | 0.97 | — | — | |
| Butyric Acid SCHEMBL29840590 | 0.97 | FFAR3 (0.93) | — | |
| Butyric Acid SCHEMBL15821495 | 0.94 | FFAR3 (0.88) | — | |
| Butyric Acid SCHEMBL6636143 | 0.94 | — | — | |
| Butyric Acid SCHEMBL27467839 | 0.94 | — | — | |
| Butyric Acid SCHEMBL1071415 | 0.94 | FFAR3 (0.94) | — | |
| Butyric Acid SCHEMBL7849456 | 0.94 | FFAR3 (0.88) | — | |
| Butyric Acid SCHEMBL15822427 | 0.94 | FFAR3 (0.88) | — | |
| Butyric Acid SCHEMBL15821425 | 0.94 | — | — | |
| Butyric Acid SCHEMBL28151029 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451834-B1 | Alpha-mannosidase and fucosidase inhibitors | MERRELL PHARMA INC (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5382709-A | IMMUNOSTIMULANTS, VIRICIDES AND ANTIMETASTATIC AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-01-17 | — | — | US | disclosed |
| US-5240707-A | 2,3,4-trihydroxy-5-(hydroxymethyl)cyclopentylamines used as immunostimulants, viricides and antimetastasis agents | MERRELL DOW PHARMACEUTICALS INC. | 1993-08-31 | — | — | US | disclosed |
| EP-0451834-A2 | Alpha-mannosidase and fucosidase inhibitors | MERRELL PHARMACEUTICALS INC. (US) | 1991-10-16 | — | — | EP | disclosed |
| EP-0069585-A1 | Color-forming sulfonamidodiphenylamines, photographic elements containing them and corresponding sulfonimide dyes | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1983-01-12 | — | — | EP | disclosed |