Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994382 | 0.80 | GRIA2 (0.32) | POLBMAPTGRIA2GRIA4 | |
| SCHEMBL8994403 | 0.78 | POLB (0.33) | POLBMAPTGRIA2GRIA4 | |
| SCHEMBL8994415 | 0.73 | ALOX5AP (0.33) | MCHR1GRIA2GRIA4APPPSEN1 | |
| SCHEMBL8994387 | 0.72 | POLB (0.34) | POLBMAPTGRIA2GRIA4PSEN1 | |
| SCHEMBL8994389 | 0.71 | ADORA1 (0.34) | POLBMAPTGRIA2GRIA4APP | |
| SCHEMBL8994414 | 0.68 | MGLL (0.36) | POLBTRPV1MGLLMAPTAPP | |
| SCHEMBL10589580 | 0.68 | KIF11 (0.44) | DHODHMAPTGRIA2GRIA4 | |
| SCHEMBL10591696 | 0.68 | KIF11 (0.44) | DHODHMAPTGRIA2GRIA4 | |
| SCHEMBL9057391 | 0.67 | GRIA2 (0.38) | GRIA2GRIA4APP | |
| SCHEMBL9423468 | 0.66 | KIF11 (0.38) | MGLLDHODHMAPTGRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594941-B1 | N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents | AMERICAN CYANAMID CO (US) | 1996-08-14 | — | — | EP | claimed |