SCHEMBL8994414

SCHEMBL8994414

N#Cc1c(Cl)c(Cl)n(COC(=O)C2CCCCC2)c1-c1ccc(C(F)(F)F)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
POLB P06746 2/20 0.36
KDM2B Q8NHM5 2/20 0.35
MAPT P10636 1/20 0.35
TRPV1 Q8NER1 2/20 0.35
APP P05067 1/20 0.35
PSEN1 P49768 1/20 0.35
PSEN2 P49810 1/20 0.35
APH1B Q8WW43 1/20 0.35
NCSTN Q92542 1/20 0.35
APH1A Q96BI3 1/20 0.35
PSENEN Q9NZ42 1/20 0.35
HPGD P15428 1/20 0.34
BIRC5 O15392 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ENPP3 O14638 2/20 0.33
ENPP2 Q13822 2/20 0.33
ENPP1 P22413 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8994481 0.95 MGLL (0.36) MGLLALDH1A1KDM4EPOLBKDM2B
SCHEMBL9222722 0.83 ADORA1 (0.35) ALDH1A1MAPTTRPV1PSEN1PSEN2
SCHEMBL8994386 0.82 PAX8 (0.35) ALDH1A1POLBMAPTL3MBTL1
SCHEMBL8994395 0.79 ALDH1A1 (0.33) ALDH1A1POLBMAPTHPGDL3MBTL1
SCHEMBL8072565 0.75 KIF11 (0.36) ALDH1A1MAPT
SCHEMBL8994415 0.74 ALOX5AP (0.33) APPPSEN1PSEN2APH1BNCSTN
SCHEMBL8994464 0.74 L3MBTL1 (0.34) MGLLALDH1A1KDM4EPOLBMAPT
SCHEMBL9059293 0.73 KIF11 (0.41) ALDH1A1KDM4EMAPTHPGD
SCHEMBL8994389 0.73 ADORA1 (0.34) POLBMAPTAPP
SCHEMBL9057391 0.72 GRIA2 (0.38) ALDH1A1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594941-B1 N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-08-14 EP claimed
EP-0594941-A1 N-substituted carbonyoxyalkylpyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID COMPANY (US) 1994-05-04 EP claimed