Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10812476 | 0.94 | TP53 (0.46) | — | |
| Zinc Ion SCHEMBL491386 | 0.94 | TP53 (0.46) | — | |
| SCHEMBL490848 | 0.94 | — | — | |
| SCHEMBL30586081 | 0.94 | TP53 (0.46) | — | |
| Isobutanol SCHEMBL28277108 | 0.77 | TP53 (0.58) | — | |
| Potassium Ion SCHEMBL30241974 | 0.74 | — | — | |
| SCHEMBL11684833 | 0.73 | TSHR (0.41) | — | |
| Potassium Ion SCHEMBL6228640 | 0.72 | — | — | |
| Potassium Ion SCHEMBL29407428 | 0.72 | — | — | |
| SCHEMBL490897 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585071-B1 | Process for making sodium acylisethionates | HOECHST CELANESE CORP (US) | 1996-07-24 | — | — | EP | claimed |
| US-5384421-A | Process for making sodium acylisethionates | HOECHST CELANESE CORPORATION (US) | 1995-01-24 | — | — | US | claimed |
| EP-0585071-A1 | Process for making sodium acylisethionates | HOECHST CELANESE CORPORATION (US) | 1994-03-02 | — | — | EP | claimed |
| US-20200170918-A1 | NATURALLY THICKENED COSMETIC CLEANING AGENTS | HENKEL AG & CO. KGAA (DE) | 2020-06-04 | — | — | US | disclosed |
| US-9895300-B2 | Mild cosmetic cleaning agent | HENKEL AG & CO. KGAA (DE) | 2018-02-20 | — | — | US | disclosed |
| US-20160287504-A1 | MILD COSMETIC CLEANING AGENT | HENKEL AG & CO. KGAA (DE) | 2016-10-06 | — | — | US | disclosed |
| EP-0585071-B1 | Process for making sodium acylisethionates | HOECHST CELANESE CORP (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5384421-A | Process for making sodium acylisethionates | HOECHST CELANESE CORPORATION (US) | 1995-01-24 | — | — | US | disclosed |
| EP-0585071-A1 | Process for making sodium acylisethionates | HOECHST CELANESE CORPORATION (US) | 1994-03-02 | — | — | EP | disclosed |