SCHEMBL6287052

SCHEMBL6287052

c1ccc(N(c2cc3ccccc3c3ccccc23)c2cc3ccccc3c3ccccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.43
ALDH1A1 P00352 6/20 0.43
HSD17B10 Q99714 4/20 0.43
HIF1A Q16665 2/20 0.43
CYP1B1 Q16678 1/20 0.43
HPRT1 P00492 3/20 0.41
TDP1 Q9NUW8 3/20 0.39
TSHR P16473 2/20 0.39
CYP2A6 P11509 1/20 0.39
APAF1 O14727 1/20 0.38
CASP3 P42574 1/20 0.38
CASP6 P55212 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
CYP1A2 P05177 3/20 0.36
KDM4E B2RXH2 2/20 0.36
CYP2C19 P33261 2/20 0.36
HPGD P15428 2/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13271325 0.96 TRPM4 (0.41) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL12012670 0.96 TRPM4 (0.41) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL9888888 0.96 TRPM4 (0.43) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL14069628 0.94 TRPM4 (0.42) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL15730661 0.92 ALDH1A1 (0.42) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL12333196 0.92 ALDH1A1 (0.42) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL13721283 0.92 ALDH1A1 (0.42) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL13720442 0.92 ALDH1A1 (0.42) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL16041533 0.91 ALDH1A1 (0.38) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL22669853 0.91 SIGMAR1 (0.43) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3489325-B1 ORGANIC ELECTROLUMINESCENT DEVICE LG DISPLAY CO LTD (KR) 2020-06-10 EP disclosed
EP-3489325-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG Display Co., Ltd. (KR) 2019-05-29 EP disclosed
EP-3045465-B1 ORGANIC LIGHT EMITTING MATERIALS UNIVERSAL DISPLAY CORP (US) 2019-01-30 EP disclosed
US-9608210-B2 Organic compound and organic light emitting diode using the same LG DISPLAY CO., LTD. (KR) 2017-03-28 US disclosed
US-9608210-B2 Organic compound and organic light emitting diode using the same LG DISPLAY CO., LTD. (KR) 2017-03-28 US disclosed
US-9590191-B2 Organic compound and organic light emitting diode using the same LG DISPLAY CO., LTD. (KR) 2017-03-07 US disclosed
US-9590191-B2 Organic compound and organic light emitting diode using the same LG DISPLAY CO., LTD. (KR) 2017-03-07 US disclosed
US-20160155956-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG DISPLAY CO., LTD. (KR) 2016-06-02 US disclosed
US-20160155956-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG DISPLAY CO., LTD. (KR) 2016-06-02 US disclosed
US-20160155957-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG DISPLAY CO., LTD. (KR) 2016-06-02 US disclosed
US-20120199820-A1 MONOAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-08-09 US disclosed
US-20120138912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
US-20120138912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
US-20120138911-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
US-20120138911-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2012-06-07 US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. 2011-11-17 US disclosed
US-6929872-B2 Organic electroluminescent devices NIPPON STEEL CHEMICAL CO., LTD. (JP) 2005-08-16 US disclosed
US-20040028944-A1 Organic electroluminescent devices NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2004-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120199820-A1 MONOAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME MAOA, ADRA1A, ADRA1D TRPM4 349/4885ALDH1A1 102/4885HSD17B10 753/4885
US-20120138911-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L TRPM4 1033/4885ALDH1A1 362/4885HSD17B10 3431/4885
US-20110278555-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L TRPM4 1033/4885ALDH1A1 362/4885HSD17B10 3431/4885
US-20120138912-A1 BISCARBAZOLE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME UQCRB, OXA1L, HBS1L TRPM4 879/4885ALDH1A1 380/4885HSD17B10 3174/4885
US-20110279020-A1 Biscarbazole Derivative, Material for Organic Electroluminescence Device and Organic Electroluminescence Device Using The Same UQCRB, OXA1L, HBS1L TRPM4 879/4885ALDH1A1 380/4885HSD17B10 3174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.