SCHEMBL8994852

SCHEMBL8994852

c1ccc(N(c2ccc(-c3ccc(N(c4ccccc4)c4ccc5c6c(cccc46)-c4ccccc4-5)s3)s2)c2ccc3c4c(cccc24)-c2ccccc2-3)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
USP2 O75604 1/20 0.35
APP P05067 1/20 0.34
POLB P06746 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PABPC1 P11940 2/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23546672 0.83 KEAP1 (0.47) CRHBPCRHR2KEAP1NFE2L2MEN1
SCHEMBL133233 0.83 KEAP1 (0.47) CRHBPCRHR2KEAP1NFE2L2MEN1
SCHEMBL15247025 0.81 CRHBP (0.46) CRHBPCRHR2KEAP1NFE2L2MEN1
SCHEMBL8994843 0.80 CYP1A2 (0.36) MEN1KMT2AAPPPOLBALDH1A1
SCHEMBL14491563 0.80 KEAP1 (0.44) CRHBPCRHR2KEAP1NFE2L2MEN1
SCHEMBL8994816 0.79 SIGMAR1 (0.41) KMT2AAPPALDH1A1TSHRHSD17B10
SCHEMBL5002787 0.77 CRHBP (0.42) CRHBPCRHR2KEAP1NFE2L2MEN1
SCHEMBL12566482 0.76 CRHBP (0.41) CRHBPCRHR2KEAP1NFE2L2MEN1
SCHEMBL23546674 0.76 CRHBP (0.41) CRHBPCRHR2KEAP1NFE2L2MEN1
SCHEMBL16282102 0.75 APP (0.32) APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187728-B2 Organic electroluminescent device and display device SONY CORPORATION (JP) 2012-05-29 US disclosed
US-8187728-B2 Organic electroluminescent device and display device SONY CORPORATION (JP) 2012-05-29 US disclosed
US-20090026935-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2009-01-29 US disclosed
US-20090026935-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2009-01-29 US disclosed