SCHEMBL133233

SCHEMBL133233

c1ccc(N(c2ccccc2)c2ccc3c4c(cccc24)-c2ccccc2-3)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.47
NFE2L2 Q16236 2/20 0.47
CRHBP P24387 2/20 0.47
CRHR2 Q13324 2/20 0.47
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
USP2 O75604 4/20 0.43
ALDH1A1 P00352 8/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
HSD17B10 Q99714 3/20 0.41
TSHR P16473 2/20 0.41
MAPK1 P28482 2/20 0.41
CASP1 P29466 2/20 0.41
HPGD P15428 1/20 0.41
HIF1A Q16665 1/20 0.41
POLB P06746 2/20 0.40
MAPT P10636 4/20 0.40
KDM4E B2RXH2 4/20 0.40
PABPC1 P11940 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23546672 1.00 KEAP1 (0.47) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL15247025 0.98 CRHBP (0.46) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL5002787 0.93 CRHBP (0.42) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL14491563 0.93 KEAP1 (0.44) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL12566482 0.92 CRHBP (0.41) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL23546674 0.92 CRHBP (0.41) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL10128557 0.90 KDM4E (0.41) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL16483981 0.90 CRHBP (0.40) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL18904410 0.90 CRHBP (0.40) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL14491574 0.90 CRHBP (0.42) KEAP1NFE2L2CRHBPCRHR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10125467-A None JP disclosed
US-20210387994-A1 SOLVENT-FREE CROSS-COUPLING REACTION, AND PRODUCTION METHOD USING SAID REACTION NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2021-12-16 US disclosed
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed
WO-2020085396-A1 SOLVENT-FREE CROSS-COUPLING REACTION, AND PRODUCTION METHOD USING SAID REACTION 国立大学法人北海道大学 2020-04-30 WO disclosed
US-10243145-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2019-03-26 US disclosed
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2019-01-29 US disclosed
US-20180212152-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180212152-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-9960358-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-9960358-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
WO-2008111543-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2008-09-18 WO disclosed
US-20080206447-A1 ORGANIC-ELECTROLUMINESCENCE-MATERIAL-CONTAINING SOLUTION, METHOD FOR FORMING ORGANIC ELECTROLUMINESCENCE THIN FILM AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2008-08-28 US disclosed
US-20080206447-A1 ORGANIC-ELECTROLUMINESCENCE-MATERIAL-CONTAINING SOLUTION, METHOD FOR FORMING ORGANIC ELECTROLUMINESCENCE THIN FILM AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2008-08-28 US disclosed
US-20070237984-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2007-10-11 US disclosed
US-20070237984-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2007-10-11 US disclosed
US-20070200123-A1 Organic Electroluminescence Display Device IDEMITSU KOSAN CO., LTD. (JP) 2007-08-30 US disclosed
US-20070200123-A1 Organic Electroluminescence Display Device IDEMITSU KOSAN CO., LTD. (JP) 2007-08-30 US disclosed
US-20070170843-A1 Organic electroluminescent device and organic electroluminescent display IDEMITSU KOSAN CO., LTD. (JP) 2007-07-26 US disclosed
US-20070170843-A1 Organic electroluminescent device and organic electroluminescent display IDEMITSU KOSAN CO., LTD. (JP) 2007-07-26 US disclosed
JP-H10125467-A ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEM INC 1998-05-15 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210387994-A1 SOLVENT-FREE CROSS-COUPLING REACTION, AND PRODUCTION METHOD USING SAID REACTION MCCC2, CTRC, DDC KEAP1 1248/4885NFE2L2 809/4885CRHBP 1814/4885
US-10243145-B2 Organic electroluminescence device and organic light emitting medium TRPA1, EPM2A, KCNN2 KEAP1 653/4885NFE2L2 135/4885CRHBP 3965/4885
US-10193077-B2 Biscarbazole derivative, material for organic electroluminescence device and organic electroluminescence device using the same UQCRB, OXA1L, HBS1L KEAP1 806/4885NFE2L2 1053/4885CRHBP 4549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.