Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994847 | 0.90 | LTB4R (0.46) | LTB4RLTB4R2THRBTHRAGAA | |
| SCHEMBL8995075 | 0.89 | LTB4R (0.48) | LTB4RLTB4R2GAARAB9ANPC1 | |
| SCHEMBL8995008 | 0.87 | NR1H4 (0.39) | LTB4RLTB4R2THRBTHRARAB9A | |
| SCHEMBL8590610 | 0.86 | LTB4R (0.48) | LTB4RLTB4R2THRBTHRAGAA | |
| SCHEMBL8995041 | 0.86 | LTB4R (0.54) | LTB4RLTB4R2GAARAB9ANPC1 | |
| SCHEMBL8995025 | 0.85 | LTB4R (0.63) | LTB4RLTB4R2RAB9ANPC1LMNA | |
| Hydrochloric Acid SCHEMBL8995049 | 0.85 | LTB4R (0.62) | LTB4RLTB4R2RAB9ANPC1LMNA | |
| SCHEMBL8590368 | 0.82 | LTB4R (0.44) | LTB4RLTB4R2GAARAB9ANPC1 | |
| SCHEMBL8593367 | 0.82 | LTB4R (0.46) | LTB4RLTB4R2GAARAB9ANPC1 | |
| SCHEMBL8994933 | 0.81 | THRB (0.43) | LTB4RLTB4R2THRBTHRASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |