Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8748025 | 0.91 | RAB9A (0.47) | NR1H4THRATHRBLTB4RNPC1 | |
| SCHEMBL8748028 | 0.91 | RAB9A (0.47) | NR1H4THRATHRBLTB4RNPC1 | |
| SCHEMBL8995004 | 0.87 | LTB4R (0.50) | LTB4RLTB4R2 | |
| SCHEMBL8994927 | 0.87 | LTB4R (0.47) | THRATHRBLTB4RNPC1PKM | |
| Hydrochloric Acid SCHEMBL8994888 | 0.86 | LTB4R (0.49) | LTB4RLTB4R2 | |
| SCHEMBL8995015 | 0.83 | ATM (0.40) | NR1H4THRATHRBMTNR1AMTNR1B | |
| SCHEMBL8995022 | 0.82 | CA1 (0.41) | NR1H4THRATHRBMAOB | |
| SCHEMBL8748089 | 0.81 | THRA (0.42) | NR1H4THRATHRBNPC1 | |
| Hydrochloric Acid SCHEMBL8994900 | 0.81 | CA1 (0.41) | NR1H4THRATHRBMAOB | |
| SCHEMBL8747936 | 0.81 | GAA (0.47) | LTB4RNPC1RAB9ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |