Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.46 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.46 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | S100B | P04271 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8994888 | 0.99 | LTB4R (0.49) | LTB4RLTB4R2PRMT1F2ST14 | |
| SCHEMBL8748028 | 0.89 | RAB9A (0.47) | LTB4RLTB4R2 | |
| SCHEMBL8748025 | 0.89 | RAB9A (0.47) | LTB4RLTB4R2 | |
| Hydrochloric Acid SCHEMBL9141516 | 0.89 | LTB4R (0.50) | LTB4RLTB4R2PRMT1F2ST14 | |
| SCHEMBL8995008 | 0.87 | NR1H4 (0.39) | LTB4RLTB4R2 | |
| SCHEMBL9699605 | 0.87 | PRMT1 (0.56) | LTB4RLTB4R2PRMT1F2ST14 | |
| Hydrochloric Acid SCHEMBL8591155 | 0.86 | LTB4R (0.50) | LTB4RLTB4R2PRMT1F2ST14 | |
| SCHEMBL8995025 | 0.86 | LTB4R (0.63) | LTB4RLTB4R2PRMT1F2ST14 | |
| Hydrochloric Acid SCHEMBL8995049 | 0.85 | LTB4R (0.62) | LTB4RLTB4R2PRMT1F2ST14 | |
| SCHEMBL8748089 | 0.84 | THRA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |