Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994992 | 0.88 | MAPT (0.47) | LTB4RLTB4R2LMNANPC1SMN1; SMN2 | |
| SCHEMBL8995041 | 0.84 | LTB4R (0.54) | LTB4RLTB4R2LMNANPC1CYP2D6 | |
| SCHEMBL8594088 | 0.83 | LTB4R (0.41) | LTB4RLTB4R2LMNANPC1SMN1; SMN2 | |
| SCHEMBL8994846 | 0.82 | LTB4R (0.53) | LTB4RLTB4R2LMNANPC1GAA | |
| SCHEMBL8994848 | 0.82 | LTB4R (0.53) | LTB4RLTB4R2LMNANPC1GAA | |
| SCHEMBL8748258 | 0.82 | GAA (0.63) | LTB4RLTB4R2LMNANPC1CYP2D6 | |
| SCHEMBL8748256 | 0.82 | GAA (0.63) | LTB4RLTB4R2LMNANPC1CYP2D6 | |
| SCHEMBL8995092 | 0.81 | LTB4R (0.43) | LTB4RLTB4R2LMNANPC1SMN1; SMN2 | |
| SCHEMBL8592789 | 0.80 | LTB4R (0.39) | LTB4RLTB4R2LMNANPC1SMN1; SMN2 | |
| SCHEMBL8994930 | 0.80 | LTB4R (0.75) | LTB4RLTB4R2LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | claimed |
| US-5488160-A | LEUKOTRIENE B4 RECEPTOR ANTAGONIST AS ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |