Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 13/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | NOS1 | P29475 | 1/20 | 0.63 |
| ▸ | LTA4H | P09960 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995361 | 0.93 | QPCT (0.69) | TBXAS1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL7303484 | 0.85 | TBXAS1 (1.00) | TBXAS1KDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL8995200 | 0.84 | TBXAS1 (0.52) | TBXAS1KDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL4131855 | 0.82 | TBXAS1 (0.70) | TBXAS1KDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL10785887 | 0.81 | KDM4E (0.72) | TBXAS1KDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL76839 | 0.81 | KDM4E (0.72) | TBXAS1KDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL8684965 | 0.81 | MAPK1 (1.00) | TBXAS1KDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL305632 | 0.81 | ALDH1A1 (0.72) | TBXAS1KDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL8690248 | 0.81 | KMT2A (0.83) | TBXAS1KDM4EALDH1A1MAPK1KMT2A | |
| SCHEMBL13246359 | 0.81 | QPCT (0.85) | TBXAS1KDM4EALDH1A1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496844-A | Indole derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0639567-A1 | INDOLE DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1995-02-22 | — | — | EP | disclosed |