Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541736 | 0.88 | LMNA (0.46) | GAALMNAALDH1A1TDP1HIF1A | |
| SCHEMBL8995416 | 0.83 | LMNA (0.41) | GAALMNAALDH1A1TDP1HIF1A | |
| SCHEMBL8674450 | 0.83 | LMNA (0.41) | GAALMNAALDH1A1TDP1HIF1A | |
| SCHEMBL8540010 | 0.74 | POLB (0.47) | GAAALDH1A1HTTTSHRPOLB | |
| SCHEMBL8541814 | 0.70 | GAA (0.55) | GAALMNAALDH1A1TDP1HTT | |
| SCHEMBL8995403 | 0.70 | GAA (0.36) | GAALMNAALDH1A1TDP1TSHR | |
| SCHEMBL10809043 | 0.68 | ALDH1A1 (0.46) | LMNAALDH1A1TDP1HTTHIF1A | |
| SCHEMBL21908843 | 0.68 | POLB (0.46) | GAALMNAALDH1A1TDP1HTT | |
| SCHEMBL8543249 | 0.66 | ALDH1A1 (0.43) | LMNAALDH1A1TDP1HTTHIF1A | |
| Acetic Acid SCHEMBL15637178 | 0.65 | TDP1 (0.38) | LMNAALDH1A1TDP1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566166-B1 | Chelants possessing ortho ligating functionality and complexes thereof | DOW CHEMICAL CO (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0570022-B1 | Chelants possessing ortho ligating functionality and complexes thereof | DOW CHEMICAL CO (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0570022-A2 | Chelants possessing ortho ligating functionality and complexes thereof | THE DOW CHEMICAL COMPANY (US) | 1993-11-18 | — | — | EP | disclosed |
| EP-0566166-A1 | Chelants possessing ortho ligating functionality and complexes thereof | THE DOW CHEMICAL COMPANY (a Delaware corporation) (US) | 1993-10-20 | — | — | EP | disclosed |