Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491675 | 0.72 | PTPN2 (0.46) | PTGS2PTPN2PTPN1PTPN5XDH | |
| SCHEMBL6862724 | 0.69 | PTPN1 (0.67) | PTGS2PTPN2PTPN1PTPN5MAPT | |
| SCHEMBL28265560 | 0.68 | ALDH1A1 (0.51) | PTGS2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL4913678 | 0.67 | PTPN1 (0.60) | PTGS2PTPN2PTPN1PTPN5MAPT | |
| SCHEMBL11781399 | 0.67 | KDM4E (0.48) | PTGS2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL8983439 | 0.65 | PTPN1 (0.55) | PTGS2PTPN2PTPN1PTPN5MAPT | |
| SCHEMBL9617482 | 0.65 | PTGS2 (0.69) | PTGS2PTPN2PTPN1PTPN5MAPT | |
| SCHEMBL10480337 | 0.64 | PTPN2 (0.48) | PTGS2PTPN2PTPN1PTPN5XDH | |
| SCHEMBL29504749 | 0.64 | TOP2A (0.62) | PTGS2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL171055 | 0.64 | TOP2A (0.62) | PTGS2MAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561143-A | ANTICHOLESTEROL AGENTS, ANTILIPEMIC AGENTS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-10-01 | — | — | US | disclosed |