Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491675 | 0.81 | PTPN2 (0.46) | PTPN2PTPN1PTPN5XDHNLRP3 | |
| SCHEMBL10480341 | 0.81 | PTPN2 (0.48) | PTPN2PTPN1PTPN5MAPTKDM4E | |
| SCHEMBL27258156 | 0.74 | PTPN2 (0.44) | PTPN2PTPN1PTPN5XDHNLRP3 | |
| SCHEMBL10480340 | 0.72 | ALDH1A1 (0.48) | PTPN2PTPN1XDHALDH1A1GAA | |
| SCHEMBL2123396 | 0.72 | MAPT (0.50) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11336715 | 0.71 | MAPT (0.51) | PTPN2PTPN1PTPN5XDHNLRP3 | |
| SCHEMBL86097 | 0.71 | MAPT (0.48) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2147325 | 0.71 | MAPT (0.48) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10744743 | 0.70 | RAB9A (0.51) | PTPN2PTPN1PTPN5XDHNLRP3 | |
| SCHEMBL11763172 | 0.70 | LMNA (0.44) | PTPN2PTPN1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822809-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1989-04-18 | — | — | US | disclosed |