Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995530 | 1.00 | CTSS (0.46) | CTSSCTSKGRIA1CTSBCTSL | |
| SCHEMBL8995548 | 0.88 | CTSS (0.52) | CTSSCTSKCTSBCTSL | |
| SCHEMBL8995562 | 0.88 | CTSS (0.52) | CTSSCTSKCTSBCTSL | |
| SCHEMBL7423272 | 0.88 | CTSS (0.52) | CTSSCTSKCTSBCTSL | |
| SCHEMBL7421065 | 0.87 | ITGB3 (0.55) | GRIA1PTPN1ITGB3ITGA2BCHRNB2 | |
| SCHEMBL7421070 | 0.87 | ITGB3 (0.55) | GRIA1PTPN1ITGB3ITGA2BCHRNB2 | |
| SCHEMBL7417133 | 0.84 | MMP2 (0.50) | GRIA1PTPN1ITGB3ITGA2BCHRNB2 | |
| SCHEMBL7418533 | 0.81 | CTSS (0.52) | CTSSCTSKCTSBCTSLALDH1A1 | |
| SCHEMBL8995549 | 0.81 | CTSS (0.52) | CTSSCTSKCTSBCTSLALDH1A1 | |
| SCHEMBL7423262 | 0.81 | CTSS (0.52) | CTSSCTSKCTSBCTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |