Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415259 | 1.00 | FOLH1 (0.52) | FOLH1CA1SIRT5SIRT2SIRT1 | |
| SCHEMBL7417452 | 0.97 | CA1 (0.51) | FOLH1CA1SIRT5SIRT2SIRT1 | |
| SCHEMBL7417109 | 0.93 | CASP1 (0.52) | FOLH1CA1SIRT2SIRT1SIRT3 | |
| SCHEMBL7414356 | 0.93 | CASP1 (0.52) | FOLH1CA1SIRT2SIRT1SIRT3 | |
| SCHEMBL8995555 | 0.91 | MEN1 (0.55) | CA1SIRT2SIRT1SIRT3TPSAB1 | |
| SCHEMBL7471588 | 0.88 | FOLH1 (0.52) | FOLH1SIRT2SIRT1TPSAB1 | |
| SCHEMBL7414657 | 0.84 | FOLH1 (0.53) | FOLH1CA1SIRT5SIRT2SIRT1 | |
| SCHEMBL7417654 | 0.84 | FOLH1 (0.53) | FOLH1CA1SIRT5SIRT2SIRT1 | |
| SCHEMBL7415256 | 0.84 | FOLH1 (0.53) | FOLH1CA1SIRT5SIRT2SIRT1 | |
| SCHEMBL7423600 | 0.83 | CTSS (0.55) | FOLH1CA1SIRT5SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |