Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 8/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417109 | 1.00 | CASP1 (0.52) | CASP1CA5ACA2CA1TPSAB1 | |
| SCHEMBL8995553 | 0.93 | FOLH1 (0.52) | CA5ACA2CA1TPSAB1FOLH1 | |
| SCHEMBL7415259 | 0.93 | FOLH1 (0.52) | CA5ACA2CA1TPSAB1FOLH1 | |
| SCHEMBL7417452 | 0.90 | CA1 (0.51) | CA5ACA2CA1TPSAB1FOLH1 | |
| SCHEMBL8995555 | 0.86 | MEN1 (0.55) | CA5ACA1TPSAB1CAPN1CAPN2 | |
| SCHEMBL7471588 | 0.84 | FOLH1 (0.52) | TPSAB1FOLH1ITGB3CAPN1CAPN2 | |
| SCHEMBL7414342 | 0.83 | CASP1 (0.53) | CASP1CA5ACA2CA1TPSAB1 | |
| SCHEMBL7414413 | 0.83 | CASP1 (0.53) | CASP1CA5ACA2CA1TPSAB1 | |
| SCHEMBL7414348 | 0.83 | CASP1 (0.53) | CASP1CA5ACA2CA1TPSAB1 | |
| SCHEMBL8995559 | 0.77 | KMT2A (0.44) | CASP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |
| WO-1993012074-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | disclosed |