Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.55 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.55 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415259 | 0.91 | FOLH1 (0.52) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL8995553 | 0.91 | FOLH1 (0.52) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL7417452 | 0.89 | CA1 (0.51) | SIRT2SIRT1SMN1; SMN2SIRT3CA1 | |
| SCHEMBL7414356 | 0.86 | CASP1 (0.52) | SIRT2SIRT1SIRT3CA1CA5A | |
| SCHEMBL7417109 | 0.86 | CASP1 (0.52) | SIRT2SIRT1SIRT3CA1CA5A | |
| SCHEMBL7409898 | 0.86 | MEN1 (0.56) | MEN1ALDH1A1HPGDKMT2ABCHE | |
| SCHEMBL7417659 | 0.86 | MEN1 (0.56) | MEN1ALDH1A1HPGDKMT2ABCHE | |
| SCHEMBL7471588 | 0.84 | FOLH1 (0.52) | SIRT2SIRT1CAPN1CAPN2TPSAB1 | |
| SCHEMBL9146621 | 0.77 | MEN1 (0.53) | MEN1ALDH1A1HPGDKMT2ABCHE | |
| SCHEMBL7385708 | 0.76 | TSHR (0.53) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |