Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995696 | 0.86 | GABRP (0.37) | ADORA3POLBTDP1L3MBTL1HCAR2 | |
| SCHEMBL29188835 | 0.80 | GABRP (0.33) | ADORA3HCAR2GABRPGABRDGABRA1 | |
| SCHEMBL8977089 | 0.78 | KDM4E (0.33) | KMO | |
| SCHEMBL8995714 | 0.76 | HCAR2 (0.41) | ADORA3L3MBTL1HCAR2GABRPGABRD | |
| SCHEMBL9784571 | 0.76 | HCAR2 (0.41) | ADORA3POLBTDP1L3MBTL1HCAR2 | |
| SCHEMBL9784563 | 0.74 | HCAR2 (0.38) | ADORA3TDP1L3MBTL1HCAR2DPP4 | |
| SCHEMBL29774205 | 0.73 | TDP1 (0.39) | TDP1HCAR2MEN1NPC1KMT2A | |
| SCHEMBL30843807 | 0.72 | ALDH1A1 (0.35) | KMOPOLBTDP1L3MBTL1HCAR2 | |
| SCHEMBL30968740 | 0.71 | HCAR2 (0.33) | ADORA3HCAR2GABRPGABRDGABRA1 | |
| SCHEMBL14900114 | 0.68 | HCAR2 (0.38) | KMOPOLBTDP1L3MBTL1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461403-B1 | Process for the preparation of dialkyl pyridine-2,3-dicarboxylate and derivatives thereof from dialkyl dichlorosucciante | AMERICAN CYANAMID CO (US) | 1996-08-28 | — | — | EP | claimed |