Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608377 | 1.00 | MMP8 (0.54) | MMP8PKMKDM4ETHRBHTT | |
| SCHEMBL608375 | 1.00 | MMP8 (0.54) | MMP8PKMKDM4ETHRBHTT | |
| SCHEMBL1812375 | 0.76 | MAPT (0.59) | MMP8PKMKDM4ETHRBHTT | |
| SCHEMBL8995753 | 0.76 | FPR2 (0.50) | MMP8ALDH1A1TSHR | |
| SCHEMBL8995757 | 0.76 | FPR2 (0.50) | MMP8ALDH1A1TSHR | |
| SCHEMBL8995750 | 0.76 | FPR2 (0.50) | MMP8ALDH1A1TSHR | |
| SCHEMBL18484564 | 0.74 | CNR2 (0.38) | MMP8ALDH1A1 | |
| SCHEMBL4426319 | 0.74 | MMP8 (0.76) | MMP8PKMKDM4ETHRBHTT | |
| SCHEMBL7857447 | 0.74 | MMP8 (0.59) | MMP8PKMKDM4ETHRBHTT | |
| SCHEMBL10493815 | 0.74 | PKM (0.60) | MMP8PKMKDM4ETHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492830-A | CONTACTING RACEMIC ESTER IN AQUEOUS MEDIUM WITH SERINE CARBOXYPEPTIDASE TO HYDROLYZE S-ENANTIOMER PREFERENTIALLY | GENZYME CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |