Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3382156 | 0.82 | HSD17B10 (0.40) | HTTHSD17B10RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL20855345 | 0.67 | USP2 (0.41) | HTTHPGDKDM4EL3MBTL1MAPT | |
| SCHEMBL20855351 | 0.67 | RAB9A (0.45) | RAB9AALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL4396806 | 0.63 | NPC1 (0.41) | HTTRAB9AALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL22911700 | 0.61 | — | — | |
| SCHEMBL24517811 | 0.61 | TP53 (0.36) | ALDH1A1LMNAGAAMAPT | |
| SCHEMBL11163932 | 0.57 | ALDH1A1 (0.49) | HSD17B10RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL938514 | 0.57 | — | — | |
| SCHEMBL367099 | 0.57 | POLB (0.56) | HSD17B10RAB9ASMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL9442103 | 0.57 | POLB (0.50) | HSD17B10RAB9AALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8225548-A | — | — | None | — | — | JP | disclosed |
| JP-H08225548-A | HERBICIDAL ISOXAZOLINE DERIVATIVE | SANKYO CO LTD | 1996-09-03 | — | — | JP | disclosed |